Research shows why immune checkpoint blockade impedes but does not stop glioblastoma progression

Like locking the door but opening windows, an immune checkpoint therapy temporarily slows glioblastoma (GBM) progression but fails to establish an effective anti-tumor microenvironment and appears to increase molecular interactions inhibiting long-term immune response, according to studies led by a UCLA research team. In the Nov. 26 issue of Nature Communications, the researchers explain why […]

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EU tech firms file formal complaint against Microsoft for bundling OneDrive with Windows

Dozens of European tech firms have accused Microsoft of abusing its dominant position in the industry due to how it aggressively pushes and bundles first-party services (OneDrive, Office 365, Teams etc.) with Windows. German cloud storage company, Nextcloud, has revealed that it officially asked the EU and German authorities to put a stop to Microsoft’s […]

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A new phenotype of LRP6 mutation

A group led by Prof. Han Dong of Peking University School of Stomatology reported for the first time hand preaxial polydactyly in patients with tooth agenesis carrying a previously unknown mutation of low-density lipoprotein receptor-related protein 6 (LRP6). The study was published November 10 in NPJ Genomic Medicine. In the study, the researchers performed whole-exome […]

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